Lennox-Gastaut Syndrome

Description:
It generally occurs in early childhood between the  2nd and 6th year of life. Patients usually have frequent seizures (different types) along with cognitive symptoms.  If child with diagnosis of LGS developed seizures before age 1 year, workup for Dravet syndrome should be considered.

Other Names & Associated Gene Mutations

  • LGS

Associated Gene Mutations
At this time there are no associated gene mutations

Useful Links & Associated Physicians

1)      URL:http://www.ncbi.nlm.nih.gov/pubmed/19588340

Associated Physicians:
–          Dr. Helen Cross: UCL Institute of Child Health, The Wolfson Centre, London, UK
–          Dr. Eleanor C Hancock: Child and Family Health Services, Goldsworth Park Health Centre, Woking, UK

2)      URL:http://www.ncbi.nlm.nih.gov/pubmed/20158289

Associated Physicians:
–          Aspasia Michoulas, MD and Kevin Farrell, MD: Division of Neurology, Department of Pediatrics, University of British Columbia and British Columbia’s Children’s Hospital, Vancouver, British Columbia, Canada.

3)      URL:http://www.ncbi.nlm.nih.gov/pubmed/19955344

Associated physicians:
–          Dr James Wheless:Department of Pediatric Neurology University of Tennessee Health Science Center, Le Bonheur Children’s Medical Center – Neuroscience Institute, Memphis, Tennessee
–          Dr Joan Conry:Children’s National Medical Center, Washington, DC
–          Dr Gregory Krauss & Dr. Antonia LoPresti:Johns Hopkins University School of Medicine, Baltimore, Maryland

4)      URL:http://www.ncbi.nlm.nih.gov/pubmed/19699154

Associated Physician:
–          Dr. Kostov Konstantin, Dr. Hrisimir Kostov and Dr. Erik Tauboll: Centre for Epilepsy, Division of Clinical Neuroscience, Oslo University Hospital—Rikshospitalet, Oslo, Norway

5)      URL: http://www.ncbi.nlm.nih.gov/pubmed/19211283

Associated Physician:
–          Dr Colin D. Ferrie: Department of Paediatric Neurology, Clarendon Wing, Leeds General Infirmary, Leeds LS2 9NS, UK
–          Dr. Amit Patel: UK Medical Advisor, Eisai Ltd, Hatfield, UK

6)      URL:http://www.ncbi.nlm.nih.gov/pubmed/19170737

Associated Physician:

–          Dr. Joan A. Conry: Department of Neurology, Children’s National Medical Center, Washington, DC, U.S.A
–          Dr. Yu-Tze Ng: Barrow Neurological Institute, St. Joseph’s Hospital Medical Center, Phoenix, Arizona, U.S.A
–          Dr. Juliann M. Paolicchi:Nationwide Children’s Hospital, Columbus, Ohio, U.S.A
–          Dr. Lydia Kernitsky: Virginia Commonwealth University Medical Center, Richmond, Virginia, U.S.A
– Dr. Wendy G. Mitchell:Children’s Hospital Los Angeles, Los Angeles, California, U.S.A

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